William K. Milsom

Emeritus

We study basic aspects of the control of breathing as well as the cardio-respiratory physiology of animals living in extreme environments

My lab has two main focuses. One group of studies is directed at determining the physiological adaptations that individual species possess that allow them to live in different environments. In particular we study respiratory, cardiovascular, thermoregulatory and metabolic adaptations for life in environments with low / high levels of oxygen, carbon dioxide, temperature, food and water. We are particularly interested in the neural control of these processes. Another group of studies is directed at determining evolutionary trends in the control of breathing, particularly the role of different chemo and mechano-receptor groups in the control of breathing pattern.

Bill Milsom's Google Scholar profile
Inter- and intra-individual variability in ventilation and respiratory chemosensitivity in stickelback and zebrafish
Physiol. Zool. Biochem. (In preparation)
Borg, K.A., Sharam, S. and Milsom, W.K
2006
Regulation of ventilation in the caiman, (Caiman crocodylus); Effects of inspired CO2 on pulmonary and upper airway chemoreceptors
J. Comp Physiol. B. 176:125-138
Tattersall, G.J., Andrade, D.V. Brito, S.P., Abe, A.S. and Milsom W.K
2006
Respiratory chemoreflexes and effects of cortical activation state: role of NMDA-type glutamate receptor mediated processes
Boon, J.A., Antignano, F.L., Stewart, S.L. and Milsom, W.K
2006
Seasonal changes in daily metabolic patterns of tegu lizards (Tupinambis merianae) placed in the cold (17°C) and dark
Physiol. Biochem. Zool. (Re-Submitted)
Milsom, W.K., Andrade, D.U., Brito, S.P., Toledo, L.F., Wang,T., and Abe, A.S
2006
The effect of age and pontine input on respiratory rhythm during hypothermia in rat brainstem-spinal cord preparations
J. Physiol. (London). (In Preparation)
Zimmer, M.B. and W.K. Milsom
2006
The effects of Riluzole on respiratory rhythm generation in neonatal rodents in vitro
Respir. Physiol. Neurobiol. (In revision)
Marshall, L.H. and Milsom, W.K
2006
The role of branchial and orobranchial O2 chemoreceptors in the control of aquatic surface respiration (ASR) in the neotropical fish tambaqui (Colossoma macropomum): Prolonged and acute responses to hypoxia
J.Exp. Biol. 209:1709-1715
Florindo, L.H., Leite, C.A.C., Kalinin, A.L., Reid, S.G., Milsom, W.K. and Rantin, F.T
2006
Vagotomy and disruption of NMDA-type glutamate receptors alters ventilation in hibernating ground squirrels
Harris, M.B. and W.K. Milsom
2006
Ventilatory roll off during sustained hypercapnia is gender specific in pekin ducks
Respir. Physiol. Neurobiol. 156:47-60
Dodd, G.A.A., Scott, G.R. and Milsom, W.K
2006
Ventilatory Systems
In: Ancient Fishes. Fish Physiology: Vol.27, (Series editors A. P. Farrell and C. J. Brauner; Volume Editors: D.J. McKenzie, A.P (Submitted)
Hedrick, M.S., Collidge, E.H., and Milsom, W.K
2006